Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | FADS1 | O60427 | 3/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29154642 | 0.87 | KDM4E (0.60) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL11743614 | 0.84 | NPC1 (0.72) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL392793 | 0.83 | NPC1 (0.70) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL28244183 | 0.83 | SLC16A3 (0.63) | NPC1RAB9AKDM4EHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11743643 | 0.81 | NPC1 (0.68) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL21446864 | 0.80 | SLC16A3 (0.64) | NPC1RAB9AKDM4EALDH1A1HDAC2 | |
| SCHEMBL11312539 | 0.80 | NPC1 (0.62) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL4511180 | 0.79 | NPC1 (0.66) | NPC1RAB9AKDM4ECASP3SENP8 | |
| SCHEMBL27334250 | 0.79 | SLC16A3 (0.43) | NPC1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL2606255 | 0.78 | NPC1 (0.64) | NPC1RAB9AKDM4ECASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100548948-C | Metal ligands and improved metal catalytic processes based thereon | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-10-14 | — | — | CN | disclosed |