Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4184863 | 1.00 | PIK3CD (0.53) | PIK3CDPIK3CGAXLMERTKMAP4K4 | |
| SCHEMBL12004856 | 0.91 | PIK3CD (0.56) | PIK3CDPIK3CGAXLMERTKMAP4K4 | |
| SCHEMBL17928750 | 0.90 | PIK3CD (0.42) | PIK3CDPIK3CGMAP4K4PIK3CAPIK3CB | |
| SCHEMBL4178361 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CGAXLMERTKMAP4K4 | |
| SCHEMBL4172305 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CGAXLMERTKMAP4K4 | |
| SCHEMBL12005750 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CGAXLMERTKMAP4K4 | |
| SCHEMBL12004449 | 0.89 | PIK3CD (0.56) | PIK3CDPIK3CGAXLMERTKPIK3CA | |
| SCHEMBL27802829 | 0.89 | PIK3CD (0.56) | PIK3CDPIK3CGAXLMERTKPIK3CA | |
| SCHEMBL4181518 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R2 | |
| SCHEMBL27781262 | 0.88 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101715453-B | Heterocyclic compounds and their uses | AMGEN INC | 2012-06-27 | — | — | CN | disclosed |
| CN-101715453-A | Heterogeneous ring compound and application thereof | AMGEN INC | 2010-05-26 | — | — | CN | disclosed |