Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781665 | 0.85 | NPC1 (0.46) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL30794762 | 0.81 | GRM5 (0.58) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3584326 | 0.81 | GRM5 (0.58) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3584320 | 0.81 | GRM5 (0.58) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL27760062 | 0.80 | GRM5 (0.45) | NPC1RAB9APOLBHCRTR2SMN1; SMN2 | |
| SCHEMBL3579281 | 0.78 | SCN9A (0.52) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3575146 | 0.78 | PROKR1 (0.51) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3575142 | 0.78 | PROKR1 (0.51) | NPC1RAB9APOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3583291 | 0.75 | ACP1 (0.41) | DPP4 | |
| Hydrochloric Acid SCHEMBL4599388 | 0.74 | ACP1 (0.40) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101558065-A | Oxazole derivatives as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2009-10-14 | — | — | CN | disclosed |