Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.54 |
| ▸ | STS | P08842 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FABP2 | P12104 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602009 | 0.82 | ELANE (0.56) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL5281549 | 0.82 | ELANE (0.64) | ELANEALDH1A1SRD5A2STSPPARG | |
| SCHEMBL27607343 | 0.82 | ELANE (0.58) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL24497333 | 0.79 | ELANE (0.53) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL11441192 | 0.79 | PPARG (0.76) | ELANEALDH1A1PPARGMEN1KMT2A | |
| SCHEMBL124917 | 0.79 | SRD5A2 (0.80) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL28949003 | 0.79 | ELANE (0.67) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL9809047 | 0.79 | SRD5A2 (0.80) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL28938440 | 0.79 | SRD5A2 (0.80) | ELANEALDH1A1SRD5A2STSGAA | |
| SCHEMBL9419497 | 0.79 | SRD5A2 (0.80) | ELANEALDH1A1SRD5A2STSGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107334920-A | A kind of compound wind-weed setose thistle anti-bladder cancer oral liquid and its preparation technology | 冯敏杰 | 2017-11-10 | — | — | CN | disclosed |
| CN-106551943-A | Compositionss containing spirostane compound and application thereof | 中国科学院上海药物研究所 | 2017-04-05 | — | — | CN | disclosed |
| CN-105012853-A | Traditional Chinese medicine composition for treating hysteromyoma, preparation method and uses thereof | LI DONGHUA | 2015-11-04 | — | — | CN | disclosed |
| CN-103183715-B | Furostan type saponin derivative and uses thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-104815140-A | Composition for preventing or/and treating diabetes and preparation method of composition | GONG YANBING | 2015-08-05 | — | — | CN | disclosed |
| CN-101744978-B | Drug composition for preventing and curing diabetes mellitus | SHANGHAI INST MATERIA MEDICA | 2013-07-17 | — | — | CN | disclosed |
| CN-103183715-A | Furostan saponin derivative and purpose thereof | SHANGHAI INST MATERIA MEDICA | 2013-07-03 | — | — | CN | disclosed |
| CN-101757073-B | Medicinal composition containing atractylodes rhizome extractive | SHANGHAI INST MATERIA MEDICA | 2013-02-27 | — | — | CN | disclosed |
| CN-101757073-A | Medicinal composition containing atractylodes rhizome extractive | SHANGHAI INST MATERIA MEDICA | 2010-06-30 | — | — | CN | disclosed |
| CN-101744978-A | Drug compound for preventing and curing diabetes mellitus | SHANGHAI INST MATERIA MEDICA | 2010-06-23 | — | — | CN | disclosed |