Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | PARP1 | P09874 | 2/20 | 0.60 |
| ▸ | CSF1R | P07333 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CTSV | O60911 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | FRK | P42685 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460872 | 0.90 | FASN (0.73) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL32665949 | 0.85 | FASN (0.70) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL27785104 | 0.84 | FASN (0.69) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL27783828 | 0.84 | FASN (0.69) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL4469573 | 0.82 | FASN (1.00) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL31061146 | 0.82 | FASN (1.00) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL18092657 | 0.81 | MAPT (0.81) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL29392327 | 0.80 | MAPT (0.68) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL19857710 | 0.80 | MAPT (0.68) | FASNMAPTHCRTR1PKMPARP1 | |
| SCHEMBL3944802 | 0.77 | MAPT (1.00) | FASNMAPTPKMPARP1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101747267-B | Method for synthesizing 4-substituted-3-chlorine-2-carbostyril | UNIV SOUTHWEST | 2011-07-13 | — | — | CN | claimed |
| CN-101747267-A | Method for synthesizing 4-substituted-3-chlorine-2-carbostyril | UNIV SOUTHWEST | 2010-06-23 | — | — | CN | claimed |
| CN-101747268-B | Method for synthesizing 4-substituted-3-bromo-2-quinolone | UNIV SOUTHWEST | 2011-07-20 | — | — | CN | disclosed |
| CN-101747267-B | Method for synthesizing 4-substituted-3-chlorine-2-carbostyril | UNIV SOUTHWEST | 2011-07-13 | — | — | CN | disclosed |
| CN-101747268-A | Method for synthesizing 4-substituted-3-bromo-2-quinolone | UNIV SOUTHWEST | 2010-06-23 | — | — | CN | disclosed |
| CN-101747267-A | Method for synthesizing 4-substituted-3-chlorine-2-carbostyril | UNIV SOUTHWEST | 2010-06-23 | — | — | CN | disclosed |