Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761097 | 0.83 | ABCC1 (0.63) | ABCC1POLBGAANPC1RAB9A | |
| SCHEMBL5538373 | 0.77 | POLB (0.55) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL5527031 | 0.74 | MAPT (0.56) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL4349380 | 0.72 | MEN1 (0.59) | POLBMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4349382 | 0.72 | GAA (0.45) | ABCC1GAANPC1RAB9AKMT2A | |
| SCHEMBL5532573 | 0.72 | ABCC1 (0.51) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL5463743 | 0.72 | MAPT (0.77) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL5538585 | 0.71 | POLB (0.52) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL5526949 | 0.71 | ABCC1 (0.63) | ABCC1POLBMAPTALDH1A1GAA | |
| SCHEMBL5529178 | 0.71 | POLB (0.55) | ABCC1POLBMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |