Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 8/20 | 0.33 |
| ▸ | SSTR1 | P30872 | 6/20 | 0.33 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28106915 | 0.88 | TDP1 (0.45) | TDP1FUCA1SLC6A1GABRA5GABRB2 | |
| Tert-Butyl Formate SCHEMBL27653367 | 0.84 | TDP1 (0.41) | TDP1SSTR4SSTR1 | |
| Tert-Butyl Formate SCHEMBL28105360 | 0.84 | TDP1 (0.41) | TDP1SSTR4SSTR1 | |
| Tert-Butyl Formate SCHEMBL28785569 | 0.84 | TDP1 (0.41) | TDP1SSTR4SSTR1 | |
| Tert-Butyl Formate SCHEMBL27653754 | 0.83 | TDP1 (0.46) | TDP1SLC6A1GABRA5GABRB2SLC6A12 | |
| Tert-Butyl Formate SCHEMBL27598188 | 0.83 | TDP1 (0.46) | TDP1SLC6A1GABRA5GABRB2SLC6A12 | |
| Tert-Butyl Formate SCHEMBL20981775 | 0.83 | TDP1 (0.46) | TDP1SLC6A1GABRA5GABRB2SLC6A12 | |
| Tert-Butyl Formate SCHEMBL28026243 | 0.81 | TDP1 (0.38) | TDP1SLC6A1GABRA5GABRB2SLC6A12 | |
| Tert-Butyl Formate SCHEMBL28265972 | 0.81 | TDP1 (0.48) | TDP1SSTR4SSTR1 | |
| Tert-Butyl Formate SCHEMBL27699264 | 0.81 | TDP1 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520292-B | Sulphonylpiperidine derivant and they are for treating the purposes of disease of front dynein mediation | 武田药品工业株式会社 | 2016-09-14 | — | — | CN | disclosed |
| CN-104520292-A | Sulfonyl piperidine derivatives and use for treating prokineticin mediated diseases | TAKEDA PHARMACEUTICAL | 2015-04-15 | — | — | CN | disclosed |
| CN-101754962-B | N-azacyclic substituted pyrrole, imidazole, triazole and tetrazole derivatives as agonists of RUP3 or GPR119 for treatment of diabetes and metabolic disorders | METABOLEX INC | 2013-12-25 | — | — | CN | disclosed |
| CN-101754962-A | N-azacyclic substituted pyrrole, imidazole, triazole and tetrazole derivatives as agonists of the RUP3 or GPR119 for the treatment of diabetes and metabolic disorders | METABOLEX INC | 2010-06-23 | — | — | CN | disclosed |