Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969119 | 0.75 | CHRM2 (0.33) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL9397953 | 0.75 | CHRM2 (0.33) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| Hydrochloric Acid SCHEMBL9427265 | 0.72 | CHRM2 (0.32) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL8970335 | 0.70 | PPM1B (0.33) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL229332 | 0.68 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL13185434 | 0.68 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL229333 | 0.68 | CHRM2 (0.42) | CHRM2CHRM4CHRM3PPM1BPTPN1 | |
| SCHEMBL8970051 | 0.68 | PPM1B (0.32) | PPM1BPTPN1PPP1CC | |
| SCHEMBL8226501 | 0.66 | — | — | |
| SCHEMBL9201745 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101781310-B | Thiofuran-pyridine [3, 2-c] contained acethydrazide derivative and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2012-07-04 | — | — | CN | disclosed |
| CN-101781310-A | Thiofuran-pyridine [3, 2-c] contained acethydrazide derivative and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2010-07-21 | — | — | CN | disclosed |