Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 2/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787159 | 0.84 | HDAC3 (0.49) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL3813790 | 0.79 | CSF1R (0.52) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL1267411 | 0.79 | CSF1R (0.49) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL1508500 | 0.74 | FFAR1 (0.62) | CSF1RHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1508369 | 0.74 | CSF1R (0.44) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL1267867 | 0.73 | HDAC3 (0.57) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL1266913 | 0.73 | NPC1 (0.58) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL2702140 | 0.73 | PDE2A (0.46) | — | |
| SCHEMBL23260548 | 0.73 | LSS (0.51) | CSF1RKITRAB9AMAPTMEN1 | |
| SCHEMBL28780861 | 0.72 | NPC1 (0.57) | CSF1RKITRAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103497188-A | Compounds modulating c-fms and/or c-kit activity and uses therefor | PLEXXIKON INC | 2014-01-08 | — | — | CN | disclosed |
| CN-101605787-B | Compounds that modulate c-fms and/or c-kit activity and uses thereof | PLEXXIKON INC | 2013-11-13 | — | — | CN | disclosed |
| CN-101605787-A | Compounds that modulate c-fms and/or c-kit activity and uses thereof | PLEXXIKON INC (US) | 2009-12-16 | — | — | CN | disclosed |