Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 20/20 | 0.78 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.78 |
| ▸ | CDK2 | P24941 | 6/20 | 0.78 |
| ▸ | PRKACA | P17612 | 5/20 | 0.78 |
| ▸ | GSK3B | P49841 | 5/20 | 0.78 |
| ▸ | DAPK3 | O43293 | 5/20 | 0.78 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.78 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.78 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.78 |
| ▸ | CDK1 | P06493 | 4/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.78 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.78 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.78 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.78 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.78 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.78 |
| ▸ | AURKA | O14965 | 3/20 | 0.78 |
| ▸ | JAK2 | O60674 | 3/20 | 0.78 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.78 |
| ▸ | PRKCG | P05129 | 3/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4293715 | 0.88 | CDC7 (1.00) | CDC7ROCK2CDK2PRKACAGSK3B | |
| Tert-Butyl Formate SCHEMBL27810083 | 0.80 | CDC7 (0.79) | CDC7ROCK2CDK2PRKACAGSK3B | |
| Tert-Butyl Formate SCHEMBL27788238 | 0.80 | CDC7 (0.79) | CDC7ROCK2CDK2PRKACAGSK3B | |
| SCHEMBL4289886 | 0.78 | CDC7 (1.00) | CDC7ROCK2CDK2PRKACAGSK3B | |
| SCHEMBL3673460 | 0.78 | CDC7 (1.00) | CDC7ROCK2CDK2PRKACAGSK3B | |
| SCHEMBL3665675 | 0.78 | CDC7 (1.00) | CDC7ROCK2CDK2PRKACAGSK3B | |
| Tert-Butyl Formate SCHEMBL27810094 | 0.78 | CDC7 (0.61) | CDC7ROCK2CDK2PRKACAGSK3B | |
| Tert-Butyl Formate SCHEMBL27788235 | 0.77 | CDC7 (0.80) | CDC7ROCK2CDK2PRKACAGSK3B | |
| SCHEMBL4300162 | 0.76 | CDC7 (1.00) | CDC7ROCK2CDK2PRKACAGSK3B | |
| SCHEMBL3667438 | 0.75 | CDC7 (0.72) | CDC7ROCK2CDK2PRKACAGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790526-A | 5-heteroaryl substituted indazoles as kinase inhibitors | ABBOTT GMBH & CO KG | 2010-07-28 | — | — | CN | disclosed |