Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 6/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | FGR | P09769 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 5/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27810172 | 0.86 | LCK (0.35) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL27813487 | 0.86 | CHRNA7 (0.37) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL27788365 | 0.75 | SRC (0.61) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL27810196 | 0.72 | SRC (0.47) | KITSRCABL1FLT3NTRK1 | |
| SCHEMBL14141815 | 0.71 | LCK (0.50) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL14141859 | 0.71 | LCK (0.52) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL27788418 | 0.71 | LCK (0.42) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL27788356 | 0.70 | SRC (0.47) | KITSRCABL1FLT3NTRK1 | |
| SCHEMBL14141723 | 0.70 | LCK (0.51) | LCKKITSRCMAPK13ABL1 | |
| SCHEMBL14141947 | 0.69 | LCK (0.47) | LCKKITSRCMAPK13ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101812060-B | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIOENGINEERING TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | claimed |
| CN-101812060-A | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD | 2010-08-25 | — | — | CN | claimed |
| CN-101812060-B | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIOENGINEERING TECHNOLOGY CO LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-101812060-A | Simple novel method for preparing high-purity Sprycel, and intermediate compound | NANJING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD | 2010-08-25 | — | — | CN | disclosed |