Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27472911 | 0.98 | TSHR (0.42) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL28003405 | 0.96 | TSHR (0.41) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL28185646 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL28774686 | 0.74 | TSHR (0.44) | TSHRMEN1KMT2A | |
| SCHEMBL23581540 | 0.73 | TSHR (0.42) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL29104398 | 0.72 | TSHR (0.42) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL27770500 | 0.72 | TSHR (0.42) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL17156312 | 0.72 | TSHR (0.34) | TSHRLMNA | |
| Hydrochloric Acid SCHEMBL29090138 | 0.71 | TSHR (0.46) | TSHRMEN1KMT2AUSP2ABCB11 | |
| SCHEMBL26635837 | 0.71 | TSHR (0.40) | TSHRMEN1KMT2AUSP2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109069368-A | HYDROPHILIC SILANES | 美国陶氏有机硅公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-101778885-B | Curable compositions composed of silanes with two hydrolyzable groups | HENKEL AG & CO KGAA | 2013-07-10 | — | — | CN | disclosed |
| CN-101778885-A | Curable compositions composed of silanes with two hydrolyzable groups | HENKEL AG & CO KGAA | 2010-07-14 | — | — | CN | disclosed |