Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16493911 | 0.79 | PTGDR2 (0.52) | PTGDR2MAPTKDM4EALDH1A1POLB | |
| SCHEMBL17949550 | 0.77 | PTGDR2 (0.55) | PTGDR2KDM4EALDH1A1POLBEPHX2 | |
| SCHEMBL3174285 | 0.76 | PTGDR2 (0.52) | PTGDR2MAPTKDM4EHDAC1HDAC8 | |
| SCHEMBL3165853 | 0.76 | PTGDR2 (0.55) | PTGDR2MAPTKDM4EHDAC1HDAC8 | |
| SCHEMBL3165962 | 0.76 | PTGDR2 (0.52) | PTGDR2KDM4EHDAC1HDAC8HDAC6 | |
| SCHEMBL27771722 | 0.76 | PTGDR2 (0.55) | PTGDR2MAPTKDM4EHDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL3159525 | 0.75 | PTGDR2 (0.51) | PTGDR2KDM4EHDAC1HDAC8HDAC6 | |
| SCHEMBL3175120 | 0.74 | PTGDR2 (0.55) | PTGDR2KDM4EHDAC1HDAC8HDAC6 | |
| SCHEMBL23126476 | 0.74 | PTGDR2 (0.51) | PTGDR2MAPTKDM4EBRD4EPHX2 | |
| SCHEMBL17949523 | 0.73 | CREBBP (0.47) | PTGDR2MAPTHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |