Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 5/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29565739 | 1.00 | CYP3A4 (0.53) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| Methane SCHEMBL11583017 | 0.98 | CYP3A4 (0.52) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL13893502 | 0.85 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL29862788 | 0.83 | TDP1 (0.45) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL227614 | 0.83 | TDP1 (0.45) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL18961264 | 0.82 | TDP1 (0.46) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL462305 | 0.81 | TDP1 (0.70) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL29709073 | 0.81 | TDP1 (0.70) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL1891516 | 0.79 | CYP3A4 (0.59) | CYP3A4TDP1ALDH1A1HPGDMAPK1 | |
| SCHEMBL1021615 | 0.79 | TDP1 (0.42) | CYP3A4TDP1ALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11498926-B2 | Tricyclic heterocycles as BET protein inhibitors | INCYTE CORPORATION (US) | 2022-11-15 | — | — | US | claimed |
| US-11427684-B2 | Photopatterned planarization layers for flexible electronics | ARES Materials, Inc. (US) | 2022-08-30 | — | — | US | claimed |
| US-20210188872-A1 | TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORTION | 2021-06-24 | — | — | US | claimed |
| US-20210147631-A1 | PHOTOPATTERNED PLANARIZATION LAYERS FOR FLEXIBLE ELECTRONICS | ARES Materials, Inc. | 2021-05-20 | — | — | US | claimed |
| EP-3781221-A1 | ZWITTERIONIC POLYMERS FOR BIOMEDICAL APPLICATIONS | The Board of Trustees of the University of Illinois (US) | 2021-02-24 | — | — | EP | claimed |
| US-20200255709-A1 | OPTICALLY CLEAR ADHESIVES USING SEMI-INTERPENETRATING POLYMER NETWORKS | ARES Materials, Inc. | 2020-08-13 | — | — | US | claimed |
| US-20200123410-A1 | METHOD FOR FORMING FLEXIBLE COVER LENS FILMS | ARES MATERIALS INC. | 2020-04-23 | — | — | US | claimed |
| US-10464947-B2 | Tricyclic heterocycles as BET protein inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2019-11-05 | — | — | US | claimed |
| WO-2019204712-A1 | ZWITTERIONIC POLYMERS FOR BIOMEDICAL APPLICATIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-10-24 | — | — | WO | claimed |
| EP-2970282-B1 | TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE HOLDINGS CORP (US) | 2019-08-21 | — | — | EP | claimed |
| US-5426204-A | Trialkoxysilane with urea, urethane, sulfide or amide linkages | CIBA-GEIGY CORPORATION (US) | 1995-06-20 | — | — | US | claimed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |
| US-5372889-A | Glass coating with improved adhesion and weather resistance | CIBA-GEIGY CORPORATION (US) | 1994-12-13 | — | — | US | claimed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5266715-A | Covalent bonding of a siloxane-urea compound to form crosslinked copolymer | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| US-5200493-A | Polyurethanes and polythiourethanes; protective coatings; oil repellents; waterproofing; antisoilants | CIBA-GEIGY CORPORATION (US) | 1993-04-06 | — | — | US | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-4342860-A | AN UNSATUREATED IMIDE IS USED WITH A DI OR POLYISOCYANATE TO FORM A POLYIMIDE POLYMER | RHONE-POULENC INDUSTRIES (FR) | 1982-08-03 | — | — | US | claimed |
| US-4342861-A | AN UNSATURATGED IMIDE AND A DI OR POLYISOCYANATE GO TO MAKE UP A POLYIMIDE POLYMER WHICH ALSO CONTAINS REPEATING AMIDE GROUPS | RHONE-POULENC INDUSTRIES (FR) | 1982-08-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188872-A1 | TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | BRD1, BRD3, BRD2 | CYP3A4 3151/4885TDP1 1389/4885ALDH1A1 4459/4885 |
| US-11498926-B2 | Tricyclic heterocycles as BET protein inhibitors | BRD1, BRD3, BRD2 | CYP3A4 3151/4885TDP1 1389/4885ALDH1A1 4459/4885 |
| US-10464947-B2 | Tricyclic heterocycles as BET protein inhibitors | BRD1, BRD3, BRD2 | CYP3A4 3151/4885TDP1 1389/4885ALDH1A1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.