Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793925 | 0.87 | PPARG (0.32) | PPARG | |
| SCHEMBL963892 | 0.86 | POLB (0.35) | PPARGNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL963893 | 0.86 | POLB (0.35) | PPARGNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL965422 | 0.83 | PPARG (0.42) | PPARGNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL965424 | 0.83 | PPARG (0.42) | PPARGNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27794135 | 0.83 | TLR8 (0.34) | PPARGNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL28785088 | 0.81 | HDAC1 (0.35) | — | |
| SCHEMBL27794146 | 0.79 | PPARG (0.36) | PPARGSMN1; SMN2 | |
| SCHEMBL27772683 | 0.79 | PPARG (0.36) | PPARGSMN1; SMN2 | |
| SCHEMBL966137 | 0.78 | POLB (0.36) | NPC1ALDH1A1RAB9ASMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101646653-A | Fused ring compounds as partial agonists of ppar-gamma | TAKEDA PHARMACEUTICAL JP | 2010-02-10 | — | — | CN | disclosed |