Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 4/20 | 0.81 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.81 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.81 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.81 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.81 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.81 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.81 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.81 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.81 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.81 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 4/20 | 0.64 |
| ▸ | CNR2 | P34972 | 3/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839032 | 0.90 | HDAC4 (1.00) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL2842461 | 0.85 | HDAC4 (0.81) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL2847316 | 0.85 | HDAC4 (0.81) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL28783018 | 0.84 | HDAC4 (0.72) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL13789650 | 0.83 | HDAC4 (0.78) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL27777137 | 0.83 | HDAC4 (0.78) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL2842478 | 0.82 | MEN1 (0.59) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL2841767 | 0.81 | HDAC4 (0.75) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL2841696 | 0.80 | HDAC4 (0.72) | HDAC4HDAC7HDAC5HDAC1HDAC8 | |
| SCHEMBL20490637 | 0.80 | HDAC4 (0.72) | HDAC4HDAC7HDAC5HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | disclosed |