Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.63 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.63 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27777116 | 0.86 | HDAC4 (0.58) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL27798374 | 0.83 | HDAC4 (0.54) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL4536216 | 0.79 | HDAC4 (1.00) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL2847290 | 0.77 | HDAC4 (0.68) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL4540010 | 0.75 | HDAC4 (0.73) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL27777325 | 0.71 | HDAC4 (0.48) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL20490635 | 0.71 | HDAC4 (0.74) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL2839652 | 0.70 | HDAC4 (0.68) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL20490631 | 0.70 | HDAC4 (0.68) | HDAC4HDAC7HDAC5HDAC6HDAC1 | |
| SCHEMBL2841130 | 0.68 | HDAC4 (0.64) | HDAC4HDAC7HDAC5HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | claimed |
| CN-101679220-A | Histone deacetylase inhibitor | METHYLGENE INC | 2010-03-24 | — | — | CN | disclosed |