Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL841976 | 1.00 | SCN9A (0.43) | SCN9ALTA4H | |
| SCHEMBL27777569 | 0.83 | SCN9A (0.43) | SCN9A | |
| SCHEMBL839590 | 0.83 | SCN9A (0.43) | SCN9A | |
| SCHEMBL840076 | 0.82 | — | — | |
| SCHEMBL27777601 | 0.82 | — | — | |
| SCHEMBL840144 | 0.80 | KCNH2 (0.45) | SCN9A | |
| SCHEMBL27798653 | 0.80 | KCNH2 (0.45) | SCN9A | |
| SCHEMBL841430 | 0.80 | SCN9A (0.45) | SCN9A | |
| SCHEMBL840784 | 0.80 | KCNH2 (0.36) | SCN9A | |
| SCHEMBL27777571 | 0.80 | KCNH2 (0.36) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687860-B | Novel n- (8-heteroaryltetrahydronaphtalene-2yl) or n- (5- heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB | 2012-07-04 | — | — | CN | disclosed |
| CN-101687860-A | Novel n- (8-heteroaryltetrahydronaphtalene-2yl) or n- (5- heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB | 2010-03-31 | — | — | CN | disclosed |