Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5846052 | 0.78 | HTRA1 (0.35) | CHRM2CHRM1CHRM3HTRA1GPR119 | |
| SCHEMBL1782809 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL7067153 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL13263378 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL7067155 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| Ethane SCHEMBL25434708 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL13293175 | 0.68 | CHRM2 (0.37) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL17033095 | 0.67 | CHRM2 (0.36) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL20337598 | 0.67 | ITGB1 (0.45) | CHRM2CHRM1CHRM3GPR119KDM4E | |
| SCHEMBL20337597 | 0.67 | ITGB1 (0.45) | CHRM2CHRM1CHRM3GPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939444-A | Process for production of optically active indoline-2-carboxylic acid or derivative thereof | MITSUBISHI GAS CHEMICAL CO | 2011-01-05 | — | — | CN | disclosed |