Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111458 | 0.93 | APP (0.53) | APPCTSSCTSKCNR2CNR1 | |
| SCHEMBL27799349 | 0.91 | APP (0.61) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL27799350 | 0.90 | APP (0.49) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL27820300 | 0.90 | APP (0.49) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL15111270 | 0.88 | APP (0.39) | APPCTSSCTSKPSEN1PSEN2 | |
| SCHEMBL27799275 | 0.88 | APP (0.48) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL27820362 | 0.88 | APP (0.47) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL27799270 | 0.87 | APP (0.47) | APPCTSSCTSKCNR2GPR88 | |
| SCHEMBL15111459 | 0.84 | APP (0.47) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27820425 | 0.84 | APP (0.61) | APPCNR2GPR88CNR1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101945848-A | Tetrasubstituted benzenes | ENVIVO PHARMACEUTICALS INC | 2011-01-12 | — | — | CN | disclosed |