Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.44 |
| ▸ | PTGIR | P43119 | 2/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821110 | 0.90 | PTGDR2 (0.50) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27799812 | 0.90 | MEN1 (0.37) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27799917 | 0.87 | HPGD (0.39) | CYP2C9ALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL27821133 | 0.86 | PTGDR2 (0.52) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27821146 | 0.85 | PTGDR2 (0.41) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27821148 | 0.85 | PTGDR2 (0.51) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27799913 | 0.84 | PTGDR2 (0.47) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27799901 | 0.83 | PTGDR2 (0.46) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27800070 | 0.82 | PTGDR2 (0.46) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR | |
| SCHEMBL27799896 | 0.80 | PTGDR2 (0.51) | PTGDR2CYP2C9CYP3A4TBXA2RPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952244-A | PGD 2The N of acceptor, N-disubstituted amido alkyl biphenyl antagonist | AMIRA PHARMACEUTICALS INC | 2011-01-19 | — | — | CN | disclosed |