Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821522 | 1.00 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1133343 | 1.00 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23581481 | 0.95 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL22472170 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL22472168 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23581502 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL11780416 | 0.93 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL1014076 | 0.89 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL23581562 | 0.88 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL28927500 | 0.86 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101938971-A | Hardening composition | DENTSPLY DETREY GMBH | 2011-01-05 | — | — | CN | disclosed |