Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 11/20 | 1.00 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 1.00 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.74 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.74 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.74 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.74 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.74 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.74 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12153261 | 0.98 | LPAR1 (0.95) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL12153260 | 0.98 | LPAR1 (0.95) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL4028122 | 0.94 | LPAR1 (0.89) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL343102 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL343473 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL7064 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL2761267 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL12973636 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL4031587 | 0.93 | LPAR1 (0.87) | LPAR1LPAR3ABCC3ABCC4ABCB11 | |
| SCHEMBL20533210 | 0.92 | LPAR1 (0.85) | LPAR1LPAR3ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |