SCHEMBL278037

SCHEMBL278037

C=CCOC(=O)NC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4975003 0.84
SCHEMBL8608133 0.82
SCHEMBL6255611 0.82 MEN1 (0.40)
SCHEMBL8832845 0.80 TSHR (0.43)
SCHEMBL11122001 0.80 TSHR (0.41)
SCHEMBL729016 0.80 MAPT (0.50)
SCHEMBL14322601 0.79 MEN1 (0.38)
SCHEMBL14322600 0.79 MEN1 (0.38)
SCHEMBL328943 0.78
SCHEMBL890269 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443486-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-03-01 EP claimed
US-8197841-B2 Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB INCORPORATED (US) 2012-06-12 US claimed
US-8133960-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US claimed
US-8083348-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2011-12-27 US claimed
JP-4732464-B2 2011-07-27 JP claimed
CN-102066986-A Lenses comprising amphiphilic multiblock copolymers BAUSCH & LOMB 2011-05-18 CN claimed
CN-101088029-B Polymerizable surfactants and their use as device forming comonomers BAUSCH & LOMB 2011-05-18 CN claimed
US-20100317816-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US claimed
US-20100317817-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US claimed
EP-2255228-A1 LENSES COMPRISING AMPHIPHILIC MULTIBLOCK COPOLYMERS Bausch & Lomb Incorporated (US) 2010-12-01 EP claimed
EP-0559784-B1 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB (US) 1996-08-21 EP claimed
US-5525691-A Surface modification of polymeric objects BAUSCH & LOMB INCORPORATED (US) 1996-06-11 US claimed
US-5364918-A Surface modification of polymer objects BAUSCH & LOMB INCORPORATED (US) 1994-11-15 US claimed
EP-0559784-A1 SURFACE-ACTIVE MACROMONOMERS. BAUSCH & LOMB (US) 1993-09-15 EP claimed
EP-0559809-A1 SURFACE MODIFICATION OF POLYMER OBJECTS. BAUSCH & LOMB (US) 1993-09-15 EP claimed
CN-1074457-A Novel crosslinking agent capable of being cured by ultraviolet rays for copolymerization BAUSCH & LOMB (US) 1993-07-21 CN claimed
US-5219965-A Adding polymerizable surfactant to monomer mixture; contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-06-15 US claimed
US-5177165-A Contact lenses BAUSCH & LOMB INCORPORATED (US) 1993-01-05 US claimed
US-5135297-A Immersing a contact lens in an aqueous dispersion of a polymerizable surfactant macromer, a crosslinker and a free radical catalyst and irradiating with UV light; wetting agents BAUSCH & LOMB INCORPORATED (US) 1992-08-04 US claimed
WO-1992009639-A2 SURFACE-ACTIVE MACROMONOMERS BAUSCH & LOMB INCORPORATED (US) 1992-06-11 WO claimed