Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 20/20 | 0.76 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.73 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.73 |
| ▸ | PRKCA | P17252 | 1/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424589 | 0.89 | PRKD1 (0.80) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1423941 | 0.87 | PRKD1 (0.80) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1424115 | 0.87 | PRKD1 (0.87) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1424196 | 0.87 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1424000 | 0.86 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1423971 | 0.85 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL3636296 | 0.85 | PRKD1 (0.85) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1424131 | 0.85 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1423897 | 0.85 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD | |
| SCHEMBL1423898 | 0.84 | PRKD1 (1.00) | PRKD1PRKD2ADRB1PRKCAPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679418-A | [2,6] naphthyridines compounds as protein kinase inhibitors | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |