Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335418 | 0.81 | MEN1 (0.51) | PTGER1MEN1KMT2ASCN4ALMNA | |
| SCHEMBL31644042 | 0.77 | SLC2A1 (0.53) | MEN1KMT2AATMLMNAKDM4E | |
| SCHEMBL9434947 | 0.77 | SLC2A1 (0.53) | MEN1KMT2AATMLMNAKDM4E | |
| SCHEMBL27553509 | 0.76 | GAA (0.52) | SLC6A4HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6630996 | 0.76 | PTGER1 (0.56) | SLC6A4PTGER1MRGPRX4 | |
| SCHEMBL27804382 | 0.76 | MEN1 (0.56) | SLC6A4HTR2CHTR2BPTGER1MEN1 | |
| SCHEMBL875817 | 0.76 | MEN1 (0.52) | MEN1KMT2AMRGPRX4LMNAKDM4E | |
| SCHEMBL11595834 | 0.76 | CYP1A2 (0.56) | KMT2AMRGPRX4LMNASMN1; SMN2TDP1 | |
| SCHEMBL20064612 | 0.75 | SLC6A4 (0.56) | SLC6A4HTR2CHTR2BPTGER1MEN1 | |
| SCHEMBL27604187 | 0.75 | SLC6A4 (0.56) | SLC6A4HTR2CHTR2BPTGER1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981023-A | Process for preparing benzo-fused dioxin derivatives | JANSSEN PHARMACEUTICA NV | 2011-02-23 | — | — | CN | disclosed |