Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Phenylacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.77 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | CES2 | O00748 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | PAM | P19021 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylacetic Acid SCHEMBL28326941 | 0.98 | AKR1B1 (0.74) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL27698943 | 0.94 | AKR1B1 (0.68) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL2146253 | 0.88 | AKR1B1 (0.81) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL7322793 | 0.88 | AKR1B1 (0.90) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL9449909 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL13618842 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL28242469 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL1330777 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL1459 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR | |
| Phenylacetic Acid SCHEMBL27758886 | 0.88 | AKR1B1 (1.00) | AKR1B1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111944763-B | CAR-T cell culture medium and culture method | 广东康盾创新产业集团股份公司 | 2023-04-07 | — | — | CN | claimed |
| CN-111944763-A | CAR-T cell culture medium and culture method | 广东康盾生物工程技术有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-103751943-A | Fire extinguishing composition containing nitrogenous organic compound | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-04-30 | — | — | CN | claimed |
| CN-101957376-A | Colloidal gold chromatography test paper for rapidly detecting guanidineacetic acid and derivatives thereof and preparation method thereof | NANTONG YISHI BIOLOG TECHNOLOGY CO LTD | 2011-01-26 | — | — | CN | claimed |
| CN-111944763-B | CAR-T cell culture medium and culture method | 广东康盾创新产业集团股份公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111944763-B | CAR-T cell culture medium and culture method | 广东康盾创新产业集团股份公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-111944763-A | CAR-T cell culture medium and culture method | 广东康盾生物工程技术有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-111944763-A | CAR-T cell culture medium and culture method | 广东康盾生物工程技术有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-103751943-B | Fire extinguishing composition containing nitrogen-containing organic compound | 湖北及安盾消防科技有限公司 | 2020-10-13 | — | — | CN | disclosed |
| CN-103751943-A | Fire extinguishing composition containing nitrogenous organic compound | XI AN JIAN RUI SAFETY EMERGENCY EQUIPMENT LTD LIABILITY COMPANY | 2014-04-30 | — | — | CN | disclosed |
| CN-101957376-A | Colloidal gold chromatography test paper for rapidly detecting guanidineacetic acid and derivatives thereof and preparation method thereof | NANTONG YISHI BIOLOG TECHNOLOGY CO LTD | 2011-01-26 | — | — | CN | disclosed |