Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.35 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805003 | 0.92 | MAPT (0.42) | SLC6A2SLC6A4SLC6A3HRH1KCNH2 | |
| SCHEMBL27804976 | 0.92 | MAPT (0.39) | SLC6A2SLC6A4SLC6A3HRH1KCNH2 | |
| SCHEMBL27825641 | 0.89 | SLC6A2 (0.35) | SLC6A2SLC6A4HTR1ASLC6A3HRH1 | |
| SCHEMBL27825610 | 0.85 | TP53 (0.45) | MAPTLMNATP53 | |
| SCHEMBL27805098 | 0.85 | PLD1 (0.47) | HRH1KCNH2MAPTLMNAHTT | |
| SCHEMBL27805016 | 0.83 | HRH1 (0.35) | SLC6A2SLC6A4SLC6A3HRH1KCNH2 | |
| SCHEMBL27805002 | 0.81 | MAPT (0.36) | SLC6A2SLC6A4SLC6A3HRH1KCNH2 | |
| SCHEMBL27804969 | 0.80 | CETP (0.40) | HRH1KCNH2 | |
| SCHEMBL27804968 | 0.80 | CETP (0.40) | HRH1KCNH2 | |
| SCHEMBL1123818 | 0.80 | POLB (0.49) | SLC6A2SLC6A4HTR1ASLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |