Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 17/20 | 0.61 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.37 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046645 | 0.85 | ZAP70 (0.70) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL1049742 | 0.84 | ZAP70 (0.69) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL1046622 | 0.83 | ZAP70 (0.67) | ZAP70SYKTTBK1TTBK2CYP1A1 | |
| SCHEMBL1046412 | 0.83 | ZAP70 (0.67) | ZAP70SYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL27806093 | 0.82 | ZAP70 (0.60) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL27826716 | 0.81 | ZAP70 (0.65) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL1048405 | 0.80 | ZAP70 (0.63) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL1047141 | 0.80 | ZAP70 (0.79) | ZAP70SYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1048533 | 0.79 | ZAP70 (0.69) | ZAP70SYKTTBK1TTBK2 | |
| SCHEMBL1049197 | 0.79 | ZAP70 (0.60) | ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101990539-A | Compounds and compositions as kinase inhibitors | IRM LLC | 2011-03-23 | — | — | CN | claimed |