Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 20/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.57 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14001685 | 0.79 | PDPK1 (0.78) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL27806429 | 0.78 | PDPK1 (0.62) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL2429160 | 0.78 | PDPK1 (0.60) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1604109 | 0.77 | PDPK1 (1.00) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL13541693 | 0.77 | PDPK1 (0.74) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1456749 | 0.76 | PDPK1 (0.64) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL2421437 | 0.75 | PDPK1 (0.56) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1456058 | 0.75 | PDPK1 (0.79) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1603480 | 0.75 | PDPK1 (0.79) | PDPK1PIK3CAPIK3CG | |
| SCHEMBL1604348 | 0.74 | PDPK1 (0.70) | PDPK1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102056926-A | Pyrrolopyridinylpyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2011-05-11 | — | — | CN | claimed |
| CN-102056926-A | Pyrrolopyridinylpyrimidin-2-ylamine derivatives | MERCK PATENT GMBH | 2011-05-11 | — | — | CN | disclosed |