Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348492 | 0.96 | TSHR (0.42) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL15189747 | 0.91 | TSHR (0.42) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL5375196 | 0.85 | TSHR (0.48) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL5138549 | 0.84 | PTGS1 (0.33) | TSHRMAPTLMNACYP3A4USP2 | |
| SCHEMBL2005039 | 0.82 | MEN1 (0.47) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL2005037 | 0.82 | MEN1 (0.47) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL16339407 | 0.81 | TSHR (0.46) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL16339406 | 0.81 | TSHR (0.46) | TSHRALDH1A1MAPTLMNACYP3A4 | |
| SCHEMBL2118190 | 0.80 | MEN1 (0.33) | CYP3A4PTGS1PPARGOPRK1ABCG2 | |
| SCHEMBL2008602 | 0.80 | MEN1 (0.50) | ALDH1A1MAPTLMNACYP3A4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231779-A1 | IN-LINE PROCESS TO PRODUCE PELLET-STABLE POLYOLEFINS | ExxonMobil Research and Engineering Company (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009082463-A1 | IN-LINE PROCESS TO PRODUCE PELLET-STABLE POLYOLEFINS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-07-02 | — | — | WO | disclosed |