Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.73 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2780404 | 0.98 | CSNK2A1 (0.74) | CSNK2A1TAAR1MAOBCYP2A6CSNK2A2 | |
| SCHEMBL30803440 | 0.85 | CSNK2A1 (1.00) | CSNK2A1TAAR1MAOBCYP2A6CSNK2A2 | |
| SCHEMBL28999643 | 0.82 | CSNK2A1 (0.50) | CSNK2A1MAOBCYP2A6BACE1FFAR1 | |
| SCHEMBL27508195 | 0.82 | CSNK2A1 (0.69) | CSNK2A1TAAR1CSNK2A2CSNK2BCSNK2A3 | |
| SCHEMBL15679162 | 0.81 | CSNK2A1 (0.49) | CSNK2A1MAOBCYP2A6CSNK2A2CSNK2B | |
| SCHEMBL2779989 | 0.81 | CSNK2A1 (0.49) | CSNK2A1MAOBCYP2A6BACE1FFAR1 | |
| SCHEMBL20187558 | 0.79 | BACE1 (0.49) | CSNK2A1MAOBCYP2A6BACE1FFAR1 | |
| SCHEMBL3789650 | 0.78 | CSNK2A1 (0.59) | CSNK2A1TAAR1BACE1DPP4LOXL2 | |
| SCHEMBL28942599 | 0.78 | CNR1 (0.47) | CSNK2A1MAOBCYP2A6BACE1 | |
| SCHEMBL27746382 | 0.78 | TDP1 (0.47) | CSNK2A1TAAR1MAOBCYP2A6BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
| EP-2029592-A1 | PHARMACEUTICAL COMPOUNDS | Astex Therapeutics Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007125325-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007125325-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016340-A1 | PHARMACEUTICAL COMPOUNDS | PKN2, PKN1, CSNK1A1 | CSNK2A1 10/4885TAAR1 1529/4885MAOB 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.