Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224840 | 0.91 | — | — | |
| Dioxane SCHEMBL27658709 | 0.88 | MEN1 (0.69) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Oxazolidine SCHEMBL13270005 | 0.87 | MEN1 (0.56) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Oxazolidine SCHEMBL27546418 | 0.87 | — | — | |
| Oxazolidine SCHEMBL130963 | 0.87 | — | — | |
| Oxazolidine SCHEMBL22743 | 0.87 | — | — | |
| Oxazolidine SCHEMBL6653116 | 0.84 | — | — | |
| Oxazolidine SCHEMBL6659443 | 0.84 | — | — | |
| Oxazolidine SCHEMBL21874428 | 0.84 | — | — | |
| Oxazolidine SCHEMBL2459396 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102356075-A | Compositions and methods for inhibition of the jak pathway | RIGEL PHARMACEUTICALS INC | 2012-02-15 | — | — | CN | claimed |
| CN-101784285-B | Compositions for ophthalmic diseases associated with hypoxia or ischemia | R TECH UENO LTD | 2012-12-05 | — | — | CN | disclosed |
| CN-102356075-A | Compositions and methods for inhibition of the jak pathway | RIGEL PHARMACEUTICALS INC | 2012-02-15 | — | — | CN | disclosed |
| CN-1809570-B | [1,2,4] triazolo [1,5-a ] pyrimidin-2-ylurea derivatives and uses thereof | NIPPON KAYAKU KK | 2011-06-22 | — | — | CN | disclosed |
| CN-101784285-A | Compositions for ophthalmic diseases associated with hypoxia or ischemia | R TECH UENO LTD | 2010-07-21 | — | — | CN | disclosed |