Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.70 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.46 |
| ▸ | PYGL | P06737 | 12/20 | 0.45 |
| ▸ | PYGM | P11217 | 9/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573156 | 0.84 | CNR2 (0.71) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL12601739 | 0.84 | CNR2 (0.71) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL12650011 | 0.83 | CNR2 (0.69) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL12601719 | 0.83 | CNR2 (0.71) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL1572488 | 0.83 | CNR2 (1.00) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL1572491 | 0.83 | CNR2 (1.00) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL1572567 | 0.72 | CNR2 (0.81) | CNR2PYGLPYGMHRH4FLT3 | |
| SCHEMBL12601700 | 0.72 | CNR2 (0.57) | CNR2SMYD3PYGLPYGMHRH4 | |
| SCHEMBL1572945 | 0.72 | CNR2 (0.81) | CNR2PYGLPYGMHRH4FLT3 | |
| SCHEMBL1572570 | 0.72 | CNR2 (0.81) | CNR2PYGLPYGMHRH4FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778819-A | Indole indane amide compounds and method as the CB2 agonist | BRISTOL MYERS SQUIBB CO | 2010-07-14 | — | — | CN | disclosed |