Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.31 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2661561 | 0.89 | CDK4 (0.37) | CYP3A4DPP4POLBKDM4EALDH1A1 | |
| SCHEMBL2661378 | 0.89 | DPP4 (0.39) | NPY1RNPY5RCYP3A4DPP4MAPT | |
| SCHEMBL2661381 | 0.87 | CDK4 (0.39) | DPP4POLBKDM4EALDH1A1MAPK1 | |
| SCHEMBL2660106 | 0.86 | KDM4E (0.39) | NPY1RNPY5RCYP3A4DPP4MAPT | |
| SCHEMBL2661260 | 0.86 | PIK3CA (0.36) | NPY1RNPY5RALOX5APFEN1POLB | |
| SCHEMBL2661001 | 0.85 | MAPK1 (0.38) | NPY1RNPY5RCYP3A4DPP4MAPT | |
| SCHEMBL2661444 | 0.85 | NPY1R (0.39) | NPY1RNPY5RCYP3A4DPP4MAPT | |
| SCHEMBL4916106 | 0.83 | NPY1R (0.42) | NPY1RNPY5RCYP3A4POLBMAPT | |
| SCHEMBL2669426 | 0.83 | NPY1R (0.40) | NPY1RNPY5RCYP3A4POLBMAPT | |
| SCHEMBL2661485 | 0.82 | MAPK1 (0.35) | DPP4POLBMAPTMAPK1BMPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | claimed |
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |