SCHEMBL27809015

SCHEMBL27809015

C[CH]c1ccc(CCc2ccc(N3CCN(C(C)=O)CC3)cn2)cc1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 18/20 0.69
RORC P51449 1/20 0.46
CYP17A1 P05093 1/20 0.45
CYP21A2 P08686 1/20 0.45
CYP11B1 P15538 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16815677 0.87 AOC3 (0.72) AOC3RORC
SCHEMBL2068345 0.87 AOC3 (0.72) AOC3RORCCYP17A1CYP21A2CYP11B1
SCHEMBL1433124 0.87 AOC3 (0.72) AOC3RORCCYP17A1CYP21A2CYP11B1
SCHEMBL28790871 0.87 AOC3 (0.72) AOC3RORCCYP17A1CYP21A2CYP11B1
SCHEMBL1433159 0.87 AOC3 (0.72) AOC3RORC
SCHEMBL1432750 0.86 AOC3 (0.74) AOC3
SCHEMBL1432625 0.86 AOC3 (0.74) AOC3
SCHEMBL27809050 0.86 AOC3 (0.71) AOC3RORCCYP17A1CYP21A2CYP11B1
SCHEMBL1432951 0.86 AOC3 (0.71) AOC3RORCCYP17A1CYP21A2CYP11B1
SCHEMBL27809218 0.84 AOC3 (0.72) AOC3RORCCYP17A1CYP21A2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102046601-A Benzene or thiophene derivative and use thereof as VAP-1 inhibitor R TECH UENO LTD 2011-05-04 CN disclosed