Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 10/20 | 0.60 |
| ▸ | BCL2L1 | Q07817 | 9/20 | 0.60 |
| ▸ | BCL2L2 | Q92843 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1112136 | 0.93 | BCL2 (0.58) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677546 | 0.92 | BCL2 (0.61) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112004 | 0.92 | BCL2 (0.66) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL27831700 | 0.89 | BCL2 (0.55) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1112021 | 0.87 | BCL2 (0.59) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677579 | 0.85 | BCL2L1 (0.69) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1111768 | 0.85 | BCL2 (0.60) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677774 | 0.84 | BCL2 (0.63) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677817 | 0.84 | BCL2 (0.61) | BCL2BCL2L1BCL2L2 | |
| SCHEMBL1677292 | 0.84 | BCL2 (0.61) | BCL2BCL2L1BCL2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102105449-A | Arylsulfonamide compounds, compositions and methods of use | GENENTECH INC | 2011-06-22 | — | — | CN | disclosed |