Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27813550 | 0.84 | MEN1 (0.46) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL14389278 | 0.81 | MEN1 (0.46) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL13098046 | 0.80 | MEN1 (0.45) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL27463958 | 0.79 | CDC25B (0.57) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL27479516 | 0.79 | CDC25B (0.57) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL6215376 | 0.77 | POLB (0.77) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL13602973 | 0.75 | MAPK1 (0.46) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL27677015 | 0.74 | MEN1 (0.63) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL27792319 | 0.72 | MEN1 (0.37) | MEN1KMT2APOLBL3MBTL1GAA | |
| SCHEMBL6769878 | 0.72 | MEN1 (0.41) | MEN1KMT2APOLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101842376-A | Tetracyclic indole derivatives and being used for the treatment of or prophylaxis of viral infections | SCHERING CORP | 2010-09-22 | — | — | CN | disclosed |