Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10159564 | 0.84 | TAAR1 (0.59) | TAAR1HTR2ACHRNB2CHRNA4HRH1 | |
| SCHEMBL479328 | 0.84 | TAAR1 (0.59) | TAAR1HTR2ACHRNB2CHRNA4HRH1 | |
| Hydrochloric Acid SCHEMBL4226728 | 0.82 | TAAR1 (0.56) | TAAR1HTR2ACHRNB2CHRNA4HRH1 | |
| Iodide SCHEMBL28728555 | 0.82 | TAAR1 (0.56) | TAAR1HTR2ACHRNB2CHRNA4HRH1 | |
| SCHEMBL28587464 | 0.76 | TAAR1 (0.50) | TAAR1HTR2ACHRNB2CHRNA4HRH1 | |
| SCHEMBL6400989 | 0.67 | CYP1A2 (0.39) | TAAR1CYP1A2MAOAMAOB | |
| SCHEMBL5189954 | 0.67 | HRH1 (0.62) | TAAR1HTR2AHRH1SLC6A4SLC6A3 | |
| SCHEMBL22620835 | 0.67 | HRH1 (0.62) | TAAR1HTR2AHRH1SLC6A4SLC6A3 | |
| SCHEMBL4672668 | 0.67 | HRH1 (0.62) | TAAR1HTR2AHRH1SLC6A4SLC6A3 | |
| SCHEMBL6287110 | 0.67 | TAAR1 (0.48) | TAAR1HTR2ACHRNB2CHRNA4HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102119142-A | Salicylamide derivatives as nicotinic alpha 7 modulators | HOFFMANN LA ROCHE | 2011-07-06 | — | — | CN | disclosed |