Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166729 | 0.89 | RXFP1 (0.64) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL12584286 | 0.83 | MAPT (0.61) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL10114157 | 0.81 | POLB (0.60) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL18166643 | 0.81 | RXFP1 (0.72) | RXFP1HSD17B10CYP1A2KDM4EMAPT | |
| SCHEMBL18166769 | 0.80 | KDM4E (0.72) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL18166652 | 0.80 | RXFP1 (0.65) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL10113978 | 0.79 | KDM4E (0.73) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL18166585 | 0.79 | KMT2A (0.60) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL18166615 | 0.79 | CYP1A2 (0.66) | RXFP1HSD17B10CYP1A2KDM4ETSHR | |
| SCHEMBL10113950 | 0.79 | KDM4E (0.78) | RXFP1HSD17B10CYP1A2KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801362-B | Methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2014-01-22 | — | — | CN | disclosed |
| CN-101801362-A | methods and compositions for treating disorders | HYDRA BIOSCIENCES INC | 2010-08-11 | — | — | CN | disclosed |