Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 5/20 | 0.64 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.64 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.62 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423591 | 0.86 | CYSLTR1 (0.67) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL10512475 | 0.82 | PDE10A (0.77) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL3296677 | 0.82 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL9818433 | 0.81 | PDE10A (0.63) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL7716689 | 0.81 | PDE10A (0.63) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL6583310 | 0.81 | CYSLTR1 (0.78) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL8734106 | 0.81 | PDE10A (0.66) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL1423720 | 0.80 | PDE10A (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL1423730 | 0.80 | PDE10A (0.70) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL1423590 | 0.80 | PDE10A (0.62) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102131798-A | Di-substituted phenyl compounds used as inhibitors of phosphodiesterase 10 | ENVIVO PHARMACEUTICALS INC | 2011-07-20 | — | — | CN | disclosed |