Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035646 | 0.88 | CNR2 (0.46) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL988746 | 0.83 | CA1 (0.53) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL1857025 | 0.81 | USP2 (0.45) | CNR2ATMCA1CA2TDP1 | |
| Methyl 3,5-Dimethylbenzoate SCHEMBL334346 | 0.80 | CNR2 (0.66) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL70232 | 0.80 | ATM (0.61) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL14107665 | 0.79 | MEN1 (0.49) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL18210850 | 0.78 | CNR2 (0.54) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL16957372 | 0.77 | KAT6A (0.49) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL2720990 | 0.77 | CNR2 (0.46) | CNR2ATMCA1CA2TDP1 | |
| SCHEMBL26151409 | 0.77 | CNR2 (0.46) | CNR2ATMCA1CA2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059943-A2 | FLUORINATION OF ORGANIC COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-05-27 | — | — | WO | disclosed |