Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27746413 | 0.85 | TDP1 (0.32) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27847386 | 0.80 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27847387 | 0.80 | TDP1 (0.43) | TDP1 | |
| SCHEMBL13620623 | 0.78 | MGAM (0.31) | — | |
| SCHEMBL7521682 | 0.78 | MGAM (0.31) | — | |
| SCHEMBL27767233 | 0.77 | — | — | |
| Tert-Butyl Formate SCHEMBL27713287 | 0.72 | TDP1 (0.56) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28793951 | 0.71 | GRIN2B (0.37) | — | |
| Tert-Butyl Formate SCHEMBL28149280 | 0.70 | TDP1 (0.59) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28758511 | 0.70 | TDP1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101910150-B | 4-benzylamino-1-carboxyacylpiperidine derivatives as CETP inhibitors useful in the treatment of diseases such as hyperlipidemia or arteriosclerosis | NOVARTIS AG | 2013-09-18 | — | — | CN | disclosed |
| CN-101910150-A | 4-benzylamino-1-carboxyacylpiperidine derivatives as CETP inhibitors useful in the treatment of diseases such as hyperlipidemia or arteriosclerosis | NOVARTIS AG | 2010-12-08 | — | — | CN | disclosed |