SCHEMBL278316

SCHEMBL278316

Oc1ccc(-c2ccc(O)c(Cl)c2)cc1Cl

nearest known ligand 0.77

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 4/20 0.77
ESR1 P03372 2/20 0.68
TSHR P16473 3/20 0.62
HSD17B10 Q99714 2/20 0.62
HSD17B1 P14061 3/20 0.61
HSD17B2 P37059 3/20 0.61
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
AHR P35869 2/20 0.55
APP P05067 2/20 0.55
ALOX5 P09917 2/20 0.54
HDAC2 Q92769 1/20 0.52
TTR P02766 1/20 0.48
HPGD P15428 1/20 0.48
AR P10275 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP1B1 Q16678 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29911026 1.00 ESR2 (0.77) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL28202577 1.00 ESR2 (0.77) ESR2ESR1TSHRHSD17B10HSD17B1
Methane SCHEMBL10594573 0.97 ESR2 (0.74) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL7906570 0.92 AHR (0.70) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL4456281 0.90 ESR2 (0.65) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL11608660 0.90 ESR2 (0.72) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL2399696 0.90 ESR2 (0.72) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL3566128 0.90 ESR2 (0.72) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL16581366 0.90 ESR2 (0.79) ESR2ESR1TSHRHSD17B10HSD17B1
SCHEMBL8677567 0.90 ESR2 (0.72) ESR2ESR1TSHRHSD17B10HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1940913-B1 METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS SABIC INNOVATIVE PLASTICS IP (NL) 2011-06-15 EP claimed
EP-1718691-B1 PROCESS FOR PREPARING POLYARYLATE HAVING HIGH THERMO-RESISTANCE AND HIGH TRANSPARENCY LG CHEMICAL LTD (KR) 2010-08-18 EP claimed
US-7737244-B2 Process for preparing polyarylate LG CHEM, LTD. (KR) 2010-06-15 US claimed
US-20090036634-A1 Process for Preparing Polyarylate SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2009-02-05 US claimed
US-7402650-B2 decreases residual salts; bivalent phenol compound and an aromatic dicarboxylic acid halogen compound react to prepare a polyarylate, and wherein a nonionic surface-active agent is added LG CHEM, LTD. (KR) 2008-07-22 US claimed
EP-1940913-A2 METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS General Electric Company (US) 2008-07-09 EP claimed
EP-1718691-A4 PROCESS FOR PREPARING POLYARYLATE HAVING HIGH THERMO-RESISTANCE AND HIGH TRANSPARENCY LG CHEMICAL LTD (KR) 2008-05-14 EP claimed
US-7348394-B2 Methods for preparing transparent articles from biphenol polycarbonate copolymers GENERAL ELECTRIC COMPANY (US) 2008-03-25 US claimed
WO-2007094638-A1 PROCESS FOR PREPARING POLYARYLATE LG CHEM, LTD. (KR) 2007-08-23 WO claimed
WO-2007053327-A2 METHODS FOR PREPARING TRANSPARENT ARTICLES FROM BIPHENOL POLYCARBONATE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2007-05-10 WO claimed
EP-1718691-A1 PROCESS FOR PREPARING POLYARYLATE HAVING HIGH THERMO-RESISTANCE AND HIGH TRANSPARENCY LG Chem Ltd. (KR) 2006-11-08 EP claimed
WO-2006080613-A1 PROCESS FOR PREPARING POLYARYLATE HAVING HIGH THERMO-RESISTANCE AND HIGH TRANSPARENCY LG CHEM, LTD. (KR) 2006-08-03 WO claimed
US-20060058495-A1 Process for preparing polyarylate having high thermo-resistance and high transparency SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2006-03-16 US claimed
EP-0524380-B1 Method of preparing aromatic polycarbonates GEN ELECTRIC (US) 1997-03-26 EP claimed
US-5235025-A Cross-linkable thermotropic liquid crystalline aromatic polyester HIMONT ITALIA S.R.L. (IT) 1993-08-10 US claimed
EP-0524380-A1 Method of preparing aromatic polycarbonates GENERAL ELECTRIC COMPANY (US) 1993-01-27 EP claimed
US-4923947-A Thermotropic liquid crystalline aromatic polyesters of disubstituted 4,4'-dihydroxydiphenylene MONTEDISON S.P.A. (IT) 1990-05-08 US claimed
EP-0324608-A2 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-19 EP claimed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP claimed
US-4841014-A LOW MELT VISCOSITY; STRONG, FLEXIBLE MOLDINGS AKZO N.V. (NL) 1989-06-20 US claimed