SCHEMBL27832016

SCHEMBL27832016

CC(O)C(C)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.49
PDCD1 Q15116 1/20 0.49
CD274 Q9NZQ7 1/20 0.49
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
KMT2A Q03164 1/20 0.48
TP53 P04637 2/20 0.46
TSHR P16473 2/20 0.46
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
RAB9A P51151 1/20 0.42
CYP4F2 P78329 1/20 0.42
CYP4A11 Q02928 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27925036 0.92 CA1 (0.55) PDCD1CD274CA1CA2CA12
SCHEMBL14723305 0.86 TSHR (0.57) MAPTPDCD1CD274CA1CA2
SCHEMBL6228340 0.86 CA1 (0.50) MAPTPDCD1CD274CA1CA2
SCHEMBL14722772 0.85 TDP1 (0.53) MAPTPDCD1CD274CA1CA2
SCHEMBL902823 0.84 CA1 (0.52) MAPTPDCD1CD274CA1CA2
SCHEMBL15524975 0.83 CA12 (0.47) MAPTPDCD1CD274CA1CA2
SCHEMBL6228537 0.82 CA1 (0.70) MAPTPDCD1CD274CA1CA2
SCHEMBL9562944 0.79 TSHR (0.55) MAPTPDCD1CD274CA1CA2
Terephthalic Acid SCHEMBL27832014 0.79 TSHR (0.67) CA1CA2CA12CA7CA9
SCHEMBL11275122 0.78 CA1 (0.50) MAPTPDCD1CD274CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102453241-A Preparation method of poly (2, 3-butylene terephthalate) SHANGHAI JUYOU CHEMICAL ENGINEERING CO LTD 2012-05-16 CN claimed
CN-102093543-A Method for preparing 2,3-polybutylece terephthalate and copolyester thereof SHANGHAI GENIUS ADVANCED MAT 2011-06-15 CN claimed
CN-102453241-A Preparation method of poly (2, 3-butylene terephthalate) SHANGHAI JUYOU CHEMICAL ENGINEERING CO LTD 2012-05-16 CN disclosed
CN-102093543-A Method for preparing 2,3-polybutylece terephthalate and copolyester thereof SHANGHAI GENIUS ADVANCED MAT 2011-06-15 CN disclosed