Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | ABL1 | P00519 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | IDE | P14735 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | HLCS | P50747 | 6/20 | 0.63 |
| ▸ | CA12 | O43570 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 5/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 5/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290232 | 0.91 | TDP1 (0.82) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21114407 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21176811 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28283183 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28119479 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL22265330 | 0.88 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL23065674 | 0.87 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7109641 | 0.87 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL19170150 | 0.87 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL20844951 | 0.87 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108120810-A | A kind of method that biotinylated probe joint protein chip finds small-molecule chemical medicine target spot | 宁波源溯生物科技有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-102095874-A | Method for searching small molecular chemical medicament target by using biotin labeling probe and protein chip | CGENETECH SUZHOU CHINA CO LTD | 2011-06-15 | — | — | CN | claimed |
| CN-110763530-B | Method for modifying selenocysteine and application thereof | 中国科学院上海有机化学研究所 | 2021-11-02 | — | — | CN | disclosed |
| CN-110763530-A | Method for modifying selenocysteine and application thereof | 中国科学院上海有机化学研究所 | 2020-02-07 | — | — | CN | disclosed |
| CN-108120810-A | A kind of method that biotinylated probe joint protein chip finds small-molecule chemical medicine target spot | 宁波源溯生物科技有限公司 | 2018-06-05 | — | — | CN | disclosed |
| CN-102095874-A | Method for searching small molecular chemical medicament target by using biotin labeling probe and protein chip | CGENETECH SUZHOU CHINA CO LTD | 2011-06-15 | — | — | CN | disclosed |