Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27812261 | 0.81 | — | — | |
| SCHEMBL27834089 | 0.78 | CTSA (0.46) | — | |
| SCHEMBL27832473 | 0.76 | — | — | |
| SCHEMBL27812628 | 0.76 | — | — | |
| SCHEMBL27832481 | 0.73 | MEN1 (0.33) | — | |
| SCHEMBL1134590 | 0.70 | SCNN1A (0.46) | — | |
| SCHEMBL1134558 | 0.70 | SCNN1A (0.46) | — | |
| SCHEMBL28100150 | 0.70 | SCNN1A (0.33) | — | |
| SCHEMBL27847820 | 0.70 | SLC9A5 (0.36) | — | |
| SCHEMBL27798425 | 0.69 | TDP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102112130-A | Pyrazine derivatives as epithelial sodium channel blockers | NOVARTIS AG | 2011-06-29 | — | — | CN | disclosed |