SCHEMBL27833409

SCHEMBL27833409

CCNC1(C(=O)C2(NCC)CC2)CC1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5177286 0.82
Hydrochloric Acid SCHEMBL842008 0.80 FFAR3 (0.35)
SCHEMBL19369950 0.80
SCHEMBL13804337 0.80
SCHEMBL12467413 0.78 NPSR1 (0.38) MGAMGAASIMGAM2
SCHEMBL1508731 0.75 MGAM (0.44) KMT2AMGAMGAASIMGAM2
SCHEMBL22134303 0.73 POLB (0.44) KMT2ASPHK1
SCHEMBL12670055 0.73
SCHEMBL23513707 0.73 FFAR3 (0.33)
SCHEMBL5673887 0.73 CYP2C19 (0.35) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102112467-B Pyrimidine derivative as kinase inhibitors IRM LLC 2014-04-30 CN disclosed
CN-102112467-A Compounds and compositions as kinase inhibitors IRM LLC 2011-06-29 CN disclosed