Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637119 | 0.87 | KMT2A (0.63) | KMT2AEPHX2FAAHPKMGAA | |
| Hydrochloric Acid SCHEMBL27943750 | 0.85 | KMT2A (0.62) | KMT2AEPHX2FAAHPKMGAA | |
| SCHEMBL72135 | 0.84 | KMT2A (0.60) | KMT2AEPHX2FAAHPKMGAA | |
| SCHEMBL27489394 | 0.83 | KMT2A (0.46) | KMT2AEPHX2GAAMEN1TSHR | |
| SCHEMBL72136 | 0.83 | KMT2A (0.59) | KMT2AEPHX2FAAHPKMGAA | |
| Hydrochloric Acid SCHEMBL70782 | 0.82 | KMT2A (0.58) | KMT2AEPHX2FAAHPKMGAA | |
| Hydrochloric Acid SCHEMBL69896 | 0.82 | KMT2A (0.58) | KMT2AEPHX2FAAHPKMGAA | |
| SCHEMBL3991264 | 0.82 | KDM4E (0.57) | KMT2AGAAMAPTEPHX1 | |
| SCHEMBL3851155 | 0.82 | KDM4E (0.59) | KMT2AEPHX2GAAMEN1L3MBTL1 | |
| SCHEMBL27851490 | 0.82 | POLB (0.48) | KMT2AGAAMEN1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036558-A | Novel piperidine derivatives as stearoyl-CoA desaturase inhibitors | FOREST LAB HOLDINGS LTD | 2011-04-27 | — | — | CN | disclosed |