Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.63 |
| ▸ | CA1 | P00915 | 5/20 | 0.63 |
| ▸ | CA9 | Q16790 | 5/20 | 0.63 |
| ▸ | CA2 | P00918 | 4/20 | 0.63 |
| ▸ | PDE4A | P27815 | 7/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.52 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851745 | 0.89 | CA12 (0.55) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL27851691 | 0.82 | CA12 (0.47) | CA12CA1CA9CA2 | |
| SCHEMBL27831428 | 0.79 | CA12 (0.61) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL27811136 | 0.79 | CA12 (0.65) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL28787743 | 0.78 | CA12 (0.60) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL27811450 | 0.76 | CA12 (0.58) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL27811132 | 0.76 | CA12 (0.56) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL27811239 | 0.74 | CA12 (0.72) | CA12CA1CA9CA2PDE4A | |
| SCHEMBL2546138 | 0.74 | PHGDH (0.65) | — | |
| SCHEMBL27811519 | 0.73 | CA12 (0.55) | CA12CA1CA9CA2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | claimed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | claimed |
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | disclosed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | disclosed |